发明公开
EP3200822A1 BINDING MOLECULES, ESPECIALLY ANTIBODIES, BINDING TO L1CAM (CD171) 审中-公开
结合分子,特别是抗体,结合L1CAM(CD171)

BINDING MOLECULES, ESPECIALLY ANTIBODIES, BINDING TO L1CAM (CD171)
摘要:
The present disclosure relates to a binding molecule binding to L1, which is capable of binding to the same L1 epitope recognized by the monoclonal antibody L1-OV52.24, and/or which competes with the monoclonal antibody L1-OV52.24 for binding to L1, wherein the variable part of the light chain of L1-OV52.24 comprises the sequence according to SEQ ID No: 1 or wherein the light chain is encoded by SEQ ID No: 3, and wherein the variable part of the heavy chain of L1-OV52.24 comprises the sequence according to SEQ ID No: 2 or wherein the heavy chain is encoded by SEQ ID No: 4, nucleic acids encoding the binding molecules, uses thereof and pharmaceutical compositions comprising the binding molecules.
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