发明公开
- 专利标题： THERAPEUTIC COMPOUNDS AND USES THEREOF
- 专利标题（中）： 治疗性化合物及其用途
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申请号： EP15848282.8申请日： 2015-10-10
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公开(公告)号： EP3204360A1公开(公告)日： 2017-08-16
- 发明人: ROMERO, F. Anthony , MAGNUSON, Steven R. , PASTOR, Richard , TSUI, Vickie Hsiao-Wei , MURRAY, Jeremy , CRAWFORD, Terry , BURDICK, Daniel J. , ALBRECHT, Brian K. , COTE, Alexandre , TAYLOR, Alexander M. , NASVESCHUK, Christopher G. , LEBLANC, Yves , HEWITT, Michael Charles , LAI, Kwong Wah , CHEN, Kevin
- 申请人： Genentech, Inc. , Constellation Pharmaceuticals, Inc.
- 申请人地址： 1 DNA Way South San Francisco, CA 94080 US
- 专利权人： Genentech, Inc.,Constellation Pharmaceuticals, Inc.
- 当前专利权人： Genentech, Inc.,Constellation Pharmaceuticals, Inc.
- 当前专利权人地址： 1 DNA Way South San Francisco, CA 94080 US
- 代理机构： Bailey, Sam Rogerson
- 优先权： PCT/CN2014/088315 20141010
- 国际公布： WO2016055028 20160414
- 主分类号： C07D223/16
- IPC分类号： C07D223/16 ; C07D243/12 ; C07D267/14 ; C07D281/10 ; A61K31/551 ; A61K31/553 ; A61K31/554 ; A61P29/00 ; A61P37/00 ; A61P35/00
摘要：
and to salts thereof, wherein A has any of the values defined in the specification, and compositions and uses thereof. The compounds are useful as inhibitors of CBP and/or EP300. Also included are pharmaceutical compositions comprising a compound of formula (I) or a pharmaceutically acceptable salt thereof, and methods of using such compounds and salts in the treatment of various CBP and/or EP300-mediated disorders.
公开/授权文献
- EP3204360B1 THERAPEUTIC COMPOUNDS AND USES THEREOF 公开/授权日：2020-08-26
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