- 专利标题: A NOVEL PURIFICATION PROCESS FOR ISOLATION AND COMMERCIAL PRODUCTION OF RECOMBINANT TNK-TPA (TENECTEPLASE)
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申请号: EP15852227申请日: 2015-10-19
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公开(公告)号: EP3209767A4公开(公告)日: 2018-03-07
- 发明人: RAGHUWANSHI ARJUN , SINGH KUMAR SHRAWAN , KUMAR ANKIT , SAHOO RANJAN MIHIR , SINGH SANJAY
- 申请人: GENNOVA BIOPHARMACEUTICALS LTD
- 专利权人: GENNOVA BIOPHARMACEUTICALS LTD
- 当前专利权人: GENNOVA BIOPHARMACEUTICALS LTD
- 优先权: IN2343MU2014 2014-10-21
- 主分类号: C12N1/14
- IPC分类号: C12N1/14
摘要:
The present invention relates to a novel process of isolating and purifying tissue plasminogen activator and its variants more specifically TNK-tPA from CHO cells and describes an industrially applicable, simple, cost effective, robust and highly efficient process of TNK-tPA purification.
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