公开(公告)号：EP3209767A4

公开(公告)日：2018-03-07

申请号：EP15852227

申请日：2015-10-19

申请人： GENNOVA BIOPHARMACEUTICALS LTD

发明人： RAGHUWANSHI ARJUN ,  SINGH KUMAR SHRAWAN ,  KUMAR ANKIT ,  SAHOO RANJAN MIHIR ,  SINGH SANJAY

IPC分类号： C12N1/14

CPC分类号： C12N9/6408

摘要： The present invention relates to a novel process of isolating and purifying tissue plasminogen activator and its variants more specifically TNK-tPA from CHO cells and describes an industrially applicable, simple, cost effective, robust and highly efficient process of TNK-tPA purification.

公开(公告)号：EP3169697A4

公开(公告)日：2017-11-08

申请号：EP15822758

申请日：2015-07-13

申请人： GENNOVA BIOPHARMACEUTICALS LTD

发明人： RAGHUWANSHI ARJUN ,  SINGH SHRAWAN KUMAR ,  THAKER NIDHIBEN ,  SHANKAR SHAGUN ,  KARDILE PAVAN ,  SINGH SANJAY

IPC分类号： C07K1/14 ,  C07K14/535 ,  C12P21/00

CPC分类号： C07K14/535 ,  A61K9/0019 ,  A61K38/00 ,  A61K38/193 ,  A61K47/02 ,  A61K47/10 ,  A61K47/12 ,  A61K47/26 ,  A61K47/48215 ,  A61K47/60 ,  C07K1/02 ,  C07K1/14 ,  C07K1/18 ,  C07K1/34

摘要： The present invention provides a novel, scalable and industrially viable downstream process for purification of recombinant human G-CSF.