利索-全球专利检索

  1. 登录
  2. 注册
发明公开
EP3219788A1 SPINOSAD HETEROLOGOUS EXPRESSION STRAIN AND CONSTRUCTION METHOD THEREOF AND USE 审中-公开
SPINOSAD异源表达菌株及其构建方法和应用

SPINOSAD HETEROLOGOUS EXPRESSION STRAIN AND CONSTRUCTION METHOD THEREOF AND USE
摘要：
The invention provides a construction method of spinosad heterologous expression strain, a spinosad heterologous expression strain obtained by the method and use thereof in preparing spinosad. The method utilizes a plurality of homologous recombination to replace the erythromycin synthetic gene cluster of Saccharopolyspora erythraea with the spinosad synthetic gene cluster and the rhamnose synthetic gene cluster, such that the Saccharopolyspora erythraea produces spinosad.
摘要（中）：

本发明提供了多杀菌素异源表达菌株的构建方法，由该方法获得的多杀菌素异源表达菌株及其在制备多杀菌素中的应用。 该方法利用多杀菌素同源重组，用多杀菌素合成基因簇和鼠李糖合成基因簇代替红色糖多孢菌红霉素合成基因簇，以使糖多孢菌红霉菌产生多杀菌素。

信息查询
Global Dossier Espacenet
0/0