发明公开
EP3221298A1 4-OXO-3,4-DIHYDRO-1,2,3-BENZOTRIAZINES AS MODULATORS OF GPR139
审中-公开
4-OXO-3,4-二氢-1,2,3-苯并三氮唑作为GPR139调节剂
- 专利标题: 4-OXO-3,4-DIHYDRO-1,2,3-BENZOTRIAZINES AS MODULATORS OF GPR139
- 专利标题(中): 4-OXO-3,4-二氢-1,2,3-苯并三氮唑作为GPR139调节剂
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申请号: EP15816275.0申请日: 2015-11-19
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公开(公告)号: EP3221298A1公开(公告)日: 2017-09-27
- 发明人: HITCHCOCK, Stephen , LAM, Betty , MONENSCHEIN, Holger , REICHARD, Holly
- 申请人: Takeda Pharmaceutical Company Limited
- 申请人地址: 1-1 Doshomachi 4-chome Chuo-ku Osaka-shi, Osaka 541-0045 JP
- 专利权人: Takeda Pharmaceutical Company Limited
- 当前专利权人: Takeda Pharmaceutical Company Limited
- 当前专利权人地址: 1-1 Doshomachi 4-chome Chuo-ku Osaka-shi, Osaka 541-0045 JP
- 代理机构: D Young & Co LLP
- 优先权: US201462082539P 20141120; US201562184729P 20150625
- 国际公布: WO2016081736 20160526
- 主分类号: C07D253/08
- IPC分类号: C07D253/08 ; A61K31/53
摘要:
The present invention provides a method for treating a disease, disorder or condition associated with GPR139 using compounds of formula 1: which are agonists of GPR139, certain compounds encompassed by formula 1, pharmaceutical compositions thereof, processes for making the compounds, and intermediates thereof.
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