发明公开
EP3240791A1 PYRROLO AND PYRAZOLOPYRIMIDINES AS UBIQUITIN-SPECIFIC PROTEASE 7 INHIBITORS
审中-公开
作为泛素特异性蛋白酶7抑制剂的吡咯和吡唑并嘧啶
- 专利标题： PYRROLO AND PYRAZOLOPYRIMIDINES AS UBIQUITIN-SPECIFIC PROTEASE 7 INHIBITORS
- 专利标题（中）： 作为泛素特异性蛋白酶7抑制剂的吡咯和吡唑并嘧啶
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申请号： EP15832772.6申请日： 2015-12-29
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公开(公告)号： EP3240791A1公开(公告)日： 2017-11-08
- 发明人: IOANNIDIS, Stephanos , TALBOT, Adam Charles , FOLLOWS, Bruce , BUCKMELTER, Alexandre Joseph , WANG, Minghua , CAMPBELL, Ann-Marie , SCHMIDT, Darby Rye , GUERIN, David Joseph , CARAVELLA, Justin A. , DIEBOLD, R. Bruce , ERICSSON, Anna , LANCIA, JR., David
- 申请人： Forma Therapeutics, Inc.
- 申请人地址： 500 Arsenal St., Suite 100 Watertown, MA 02472 US
- 专利权人： Forma Therapeutics, Inc.
- 当前专利权人： Forma Therapeutics, Inc.
- 当前专利权人地址： 500 Arsenal St., Suite 100 Watertown, MA 02472 US
- 代理机构： Harris, Jennifer Lucy
- 优先权： US201462098141P 20141230
- 国际公布： WO2016109515 20160707
- 主分类号： C07D487/04
- IPC分类号： C07D487/04 ; A61K31/519
摘要：
The invention relates to inhibitors of USP7 inhibitors useful in the treatment of cancers, neurodegenerative diseases, immunological disorders, inflammatory disorders, cardiovascular diseases, ischemic diseases, viral infections and diseases, and bacterial infections and diseases, having the Formula: where m, n, X1, X2, R1-R5, R5′ and R6 are described herein.
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