- 专利标题: NITRIC OXIDE-RELEASING PRODRUG MOLECULE
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申请号: EP16843639.2申请日: 2016-09-06
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公开(公告)号: EP3348548A1公开(公告)日: 2018-07-18
- 发明人: GE, Jian , LI, Yunfei , ZHANG, Zhen , WANG, Yijin , WANG, Jiamiao , CHENG, Tao
- 申请人: Zhejiang Huahai Pharmaceutical Co., Ltd , Shanghai Synergy Pharmaceutical Sciences Co., Ltd
- 申请人地址: Xunqiao Linhai Taizhou, Zhejiang 317024 CN
- 专利权人: Zhejiang Huahai Pharmaceutical Co., Ltd,Shanghai Synergy Pharmaceutical Sciences Co., Ltd
- 当前专利权人: Zhejiang Huahai Pharmaceutical Co., Ltd,Shanghai Synergy Pharmaceutical Sciences Co., Ltd
- 当前专利权人地址: Xunqiao Linhai Taizhou, Zhejiang 317024 CN
- 代理机构: Graf von Stosch Patentanwaltsgesellschaft mbH
- 优先权: CN201510563200 20150907
- 国际公布: WO2017041701 20170316
- 主分类号: C07D239/91
- IPC分类号: C07D239/91 ; C07D217/24 ; A61K31/517 ; A61P9/00
摘要:
Provided are a type of compounds that can be used for treating cardiovascular diseases and compositions containing the compounds. The compounds and the compositions can improve lipid metabolism disorders by increasing high-density lipoprotein cholesterol in blood; in addition, the compounds and the compositions can also release nitric oxide, and reduce the onset risk of cardiovascular diseases by means of relaxing blood vessels, lowering blood pressure, inhibiting platelet adhesion and aggregation and maintaining vascular tension, and thus play an important role in preventing and treating the occurrence and development of cardiovascular diseases.
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