- 专利标题： ANDROGEN RECEPTOR MODULATING COMPOUNDS
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申请号： EP18163765.3申请日： 2010-10-27
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公开(公告)号： EP3369732A1公开(公告)日： 2018-09-05
- 发明人: WOHLFAHRT, Gerd , TÖRMÄKANGAS, Olli , KARJALAINEN, Arja , KNUUTTILA, Pia , HOLM, Patrik , RASKU, Sirpa , VESALAINEN, Anniina , SALO, Harri , HÖGLUND, Lisa
- 申请人： ORION CORPORATION
- 申请人地址： Orionintie 1 02200 Espoo FI
- 专利权人： ORION CORPORATION
- 当前专利权人： ORION CORPORATION
- 当前专利权人地址： Orionintie 1 02200 Espoo FI
- 代理机构： J A Kemp
- 优先权： US25515909P 20091027
- 主分类号： C07D403/12
- IPC分类号： C07D403/12 ; C07D401/14 ; C07D405/14 ; C07D413/14 ; C07D401/12 ; C07D231/12 ; C07D471/12 ; C07D487/04 ; C07D513/04
摘要：
Compounds of formula (I) wherein R 1 to R 16 , A. B and E are as defined in the claims and pharmaceutically acceptable salts and esters thereof, are disclosed. The compounds of formula ( I ) possess utility as tissue-selective androgen receptor modulators (SARM) and are particularly useful as medicaments in the treatment of prostate cancer and other AR dependent conditions and diseases where AR antagonism is desired.
公开/授权文献
- EP3369732B1 ANDROGEN RECEPTOR MODULATING COMPOUNDS 公开/授权日：2021-05-26
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