发明公开
- 专利标题: NOVEL PROSTAGLANDIN DERIVATIVE
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申请号: EP17796123.2申请日: 2017-05-09
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公开(公告)号: EP3456710A1公开(公告)日: 2019-03-20
- 发明人: YASUDA, Arata , MATSUMURA, Yasushi , SAWADA, Kazuyoshi , NANBA, Hiroyoshi , TAGUCHI, Kazuki
- 申请人: AGC INC. , Nippon Zoki Pharmaceutical Co., Ltd.
- 申请人地址: 5-1, Marunouchi 1-chome, Chiyoda-ku, Tokyo 1008405 JP
- 专利权人: AGC INC.,Nippon Zoki Pharmaceutical Co., Ltd.
- 当前专利权人: AGC INC.,Nippon Zoki Pharmaceutical Co., Ltd.
- 当前专利权人地址: 5-1, Marunouchi 1-chome, Chiyoda-ku, Tokyo 1008405 JP
- 代理机构: Müller-Boré & Partner Patentanwälte PartG mbB
- 优先权: JP2016094196 20160509
- 国际公布: WO2017195762 20171116
- 主分类号: C07C405/00
- IPC分类号: C07C405/00 ; A61K31/5575 ; A61K47/40 ; A61P7/02 ; A61P9/08 ; A61P9/10 ; A61P43/00
摘要:
The present invention relates to a novel prostaglandin derivative having an alkynyl group on ω-chain, particularly, a novel prostaglandin derivative having a double bond at the 2-position and an alkynyl group on the ω-chain and a medicament containing the compound as an active ingredient.
According to the present invention, a compound represented by the formula (1) or a pharmaceutically acceptable salt thereof;
wherein each symbol is as defined in the present specification, or a cyclodextrin clathrate compound thereof, and a medicament containing the compound as an active ingredient, particularly, a medicament for the prophylaxis or treatment of a blood flow disorder associated with spinal canal stenosis or chronic arterial occlusion, can be provided.
According to the present invention, a compound represented by the formula (1) or a pharmaceutically acceptable salt thereof;
wherein each symbol is as defined in the present specification, or a cyclodextrin clathrate compound thereof, and a medicament containing the compound as an active ingredient, particularly, a medicament for the prophylaxis or treatment of a blood flow disorder associated with spinal canal stenosis or chronic arterial occlusion, can be provided.
公开/授权文献
- EP3456710B1 NOVEL PROSTAGLANDIN DERIVATIVE 公开/授权日:2021-06-30
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