- 专利标题： PHENYLATE DERIVATIVE, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION AND USES THEREOF
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申请号： EP17802122.6申请日： 2017-05-23
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公开(公告)号： EP3459926A1公开(公告)日： 2019-03-27
- 发明人: FENG, Zhiqiang , CHEN, Xiaoguang , YANG, Yang , ZHOU, Chuan , LAI, Fangfang , JI, Ming , JIN, Xiaofeng , XUE, Nina , ZHENG, Yi , CHEN, Hao , LI, Ling
- 申请人： Institute of Materia Medica, Chinese Academy of Medical Sciences
- 申请人地址： No. 1, Xian Nong Tan Street Xuanwu District Beijing 100050 CN
- 专利权人： Institute of Materia Medica, Chinese Academy of Medical Sciences
- 当前专利权人： Institute of Materia Medica, Chinese Academy of Medical Sciences
- 当前专利权人地址： No. 1, Xian Nong Tan Street Xuanwu District Beijing 100050 CN
- 代理机构： Stephens, Clare Jean
- 优先权： CN201610343960 20160523
- 国际公布： WO2017202276 20171130
- 主分类号： C07C43/174
- IPC分类号： C07C43/174 ; C07C43/235 ; C07D319/16 ; A61K31/03 ; A61K31/075 ; A61K31/357 ; A61P35/00
摘要：
The present invention discloses a phenylate derivative, a preparation method therefor, and a pharmaceutical composition and uses thereof. Specifically, the invention relates to phenylate derivatives represented by formula (I), a pharmaceutically-acceptable salt thereof, a stereoisomer thereof, a preparation method therefor, a pharmaceutical composition containing the one or more compounds, and uses of the compounds in treating diseases related to PD-1/PD-L1 signal channels, such as cancers, infectious diseases and autoimmune diseases.
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