公开(公告)号：EP3459926A1

公开(公告)日：2019-03-27

申请号：EP17802122.6

申请日：2017-05-23

申请人： Institute of Materia Medica, Chinese Academy of Medical Sciences

发明人： FENG, Zhiqiang ,  CHEN, Xiaoguang ,  YANG, Yang ,  ZHOU, Chuan ,  LAI, Fangfang ,  JI, Ming ,  JIN, Xiaofeng ,  XUE, Nina ,  ZHENG, Yi ,  CHEN, Hao ,  LI, Ling

IPC分类号： C07C43/174 ,  C07C43/235 ,  C07D319/16 ,  A61K31/03 ,  A61K31/075 ,  A61K31/357 ,  A61P35/00

摘要： The present invention discloses a phenylate derivative, a preparation method therefor, and a pharmaceutical composition and uses thereof. Specifically, the invention relates to phenylate derivatives represented by formula (I), a pharmaceutically-acceptable salt thereof, a stereoisomer thereof, a preparation method therefor, a pharmaceutical composition containing the one or more compounds, and uses of the compounds in treating diseases related to PD-1/PD-L1 signal channels, such as cancers, infectious diseases and autoimmune diseases.