- 专利标题: SULFONAMIDE COMPOUND OR SALT THEREOF
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申请号: EP17806708.8申请日: 2017-05-30
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公开(公告)号: EP3466934A1公开(公告)日: 2019-04-10
- 发明人: MIYAHARA, Seiji , UENO, Hiroyuki , HARA, Shoki , OGINO, Yoshio
- 申请人: Taiho Pharmaceutical Co., Ltd.
- 申请人地址: 1-27, Kandanishiki-cho Chiyoda-ku, Tokyo 101-8444 JP
- 专利权人: Taiho Pharmaceutical Co., Ltd.
- 当前专利权人: Taiho Pharmaceutical Co., Ltd.
- 当前专利权人地址: 1-27, Kandanishiki-cho Chiyoda-ku, Tokyo 101-8444 JP
- 代理机构: Herzog, Fiesser & Partner Patentanwälte PartG mbB
- 优先权: JP2016109609 20160531
- 国际公布: WO2017209155 20171207
- 主分类号: C07D249/04
- IPC分类号: C07D249/04 ; A61K31/4245 ; A61K31/428
摘要:
The present invention provides a novel sulfonamide compound having a ribonucleotide reductase inhibitory activity or a salt thereof, and a pharmaceutical composition containing the same as an active ingredient.
A compound represented by Formula (I) [wherein, X 1 represents an oxygen atom or the like; X 2 represents an oxygen atom; X 3 represents -NH-; X 4 represents a hydrogen atom or the like; R 1 represents -C(R 11 )(R 12 )- or the like; R 11 and R 12 are the same or different and each represents a hydrogen atom or the like; R 2 represents an optionally substituted C 6 -C 14 aromatic hydrocarbon group or the like; R 3 represents an optionally substituted C 6 -C 14 aromatic hydrocarbon group or the like; R 4 represents a hydrogen atom or the like] or a salt thereof.
A compound represented by Formula (I) [wherein, X 1 represents an oxygen atom or the like; X 2 represents an oxygen atom; X 3 represents -NH-; X 4 represents a hydrogen atom or the like; R 1 represents -C(R 11 )(R 12 )- or the like; R 11 and R 12 are the same or different and each represents a hydrogen atom or the like; R 2 represents an optionally substituted C 6 -C 14 aromatic hydrocarbon group or the like; R 3 represents an optionally substituted C 6 -C 14 aromatic hydrocarbon group or the like; R 4 represents a hydrogen atom or the like] or a salt thereof.
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