- 专利标题： ANTI-PD-1 ANTIBODIES, METHOD FOR PRODUCING SAME AND METHOD FOR USING SAME
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申请号： EP17828049.1申请日： 2017-07-04
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公开(公告)号： EP3486257A1公开(公告)日： 2019-05-22
- 发明人: EKIMOVA, Viktoriia Mikhailovna , KORZHAVIN, Dmitry Valeryevich , CHERNYKH, Yulia Sergeevna , NEMANKIN, Timofey Aleksandrovich , SOLOVYEV, Valery Vladimirovich , VLADIMIROVA, Anna Konstantinovna , BULANKINA, Irina Andreevna , DIDUK, Sergei Vasilyevich , EROSHOVA, Anna Vladimirovna , USTIUGOV, Iakov Iurevich , ARTIUKHOVA, Marina Vladimirovna , ULITIN, Andrei Borisovich , IVANOV, Roman Alekseevich , MOROZOV, Dmitry Valentinovich
- 申请人： Joint Stock Company "Biocad"
- 申请人地址： Liter A bld. 34 ul. Svyazi Strelna Petrodvortsoviy District St.Petersburg 198515 RU
- 专利权人： Joint Stock Company "Biocad"
- 当前专利权人： Joint Stock Company "Biocad"
- 当前专利权人地址： Liter A bld. 34 ul. Svyazi Strelna Petrodvortsoviy District St.Petersburg 198515 RU
- 代理机构： De Anna, Pier Luigi
- 优先权： RU2016128487 20160713
- 国际公布： WO2018013017 20180118
- 主分类号： C07K16/28
- IPC分类号： C07K16/28 ; C12N15/13 ; C12N15/63 ; A61K39/395
摘要：
The present invention relates to biotechnology and comprises isolated monoclonal antibodies, in particular human monoclonal antibodies, which specifically bind to PD-1 with high affinity. The antibodies according to the invention may be chimeric, humanized or human antibodies, or antigen-binding fragments thereof, and may be used as a medicinal agent in oncology and immuno-oncology, for treating diseases associated with various cell proliferation or development disorders. The invention also relates to methods for producing said antibodies and a method for treating human diseases using said antibodies.
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