- 专利标题: RECOMBINANT MICROORGANISM, AND PRODUCTION METHOD OF PYRIDOXAMINE, OR SALT THEREOF, USING SAID RECOMBINANT MICROORGANISM
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申请号: EP18797661.8申请日: 2018-05-11
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公开(公告)号: EP3623471A1公开(公告)日: 2020-03-18
- 发明人: TATENO, Toshihiro , HIDESAKI, Tomonori , ARAKI, Tadashi , SHINDO, Atsunori , MATSUMOTO, Yoshiko , MIYATA, Toshio , HONJO, Masaru
- 申请人: Mitsui Chemicals, Inc. , Renascience Co., Ltd.
- 申请人地址: 5-2, Higashi-Shimbashi 1-chome Minato-ku Tokyo 105-7122 JP
- 专利权人: Mitsui Chemicals, Inc.,Renascience Co., Ltd.
- 当前专利权人: Mitsui Chemicals, Inc.,Renascience Co., Ltd.
- 当前专利权人地址: 5-2, Higashi-Shimbashi 1-chome Minato-ku Tokyo 105-7122 JP
- 代理机构: Mewburn Ellis LLP
- 优先权: JP2017095572 20170512
- 国际公布: WO2018207930 20181115
- 主分类号: C12N15/09
- IPC分类号: C12N15/09 ; C12N1/21 ; C12P17/12
摘要:
Provided are a recombinant microorganism comprising: a gene encoding a pyridoxine oxidase; and a gene encoding a pyridoxamine synthetase having an enzymatic activity of synthesizing pyridoxamine from pyridoxal, in which each of the gene encoding a pyridoxine oxidase and the gene encoding a pyridoxamine synthetase is introduced from outside of a bacterial cell, or is endogenous to the bacterial cell and has an enhanced expression, and a method of producing pyridoxamine or a salt thereof from pyridoxine or a salt thereof using the recombinant microorganism.
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