发明公开
- 专利标题： INDUCER FOR INDUCING MESENCHYMAL STEM CELLS TO DIFFERENTIATE INTO ISLET CELLS
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申请号： EP20838869.4申请日： 2020-05-25
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公开(公告)号： EP4092106A1公开(公告)日： 2022-11-23
- 发明人: ZHANG, Bingqiang , CHEN, Mengmeng , LI, Cuicui , WANG, Erpu , WANG, Fubin , ZOU, Wei , FU, Xueqi , LIU, Cuijuan
- 申请人： Qingdao Restore Biotechnology Co., Ltd.
- 申请人地址： CN Qingdao, Shandong 266000 Floor 1 and 2, Building 7, Incubation Center Qingdao Blue Biomedical Industrial Park No. 368 Hedong Road High-Tech Zone
- 代理机构： Cabinet Chaillot
- 优先权： CN202010032047 20200113
- 国际公布： WO2021143001 20210722
- 主分类号： C12N5/071
- IPC分类号： C12N5/071 ; C12N5/0775
摘要：
The present invention belongs to the field of biomedicine, and relates to an inducer for inducing a mesenchymal stem cell to differentiate into an islet cell. An inducer for inducing a mesenchymal stem cell to differentiate into an islet cell consisted of the following components: GLP-1, parathyroid hormone, paracetamol, rapamycin, icariin, trametinib, EPO and VEGF. Each component in a inducer for inducing a mesenchymal stem cell to differentiate into an islet cell of the present invention is safe and non-toxic, requiring fewer steps and short time to induce differentiation, with high induction efficiency.
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