- 专利标题： TETRAHYDROQUINOLINE DERIVATIVE AND MEDICINAL USE THEREOF
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申请号： EP21911025.1申请日： 2021-12-24
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公开(公告)号： EP4269392A1公开(公告)日： 2023-11-01
- 发明人: ASABA, Ken Nunettsu , TAKAHASHI,Takehiro , YAMAMOTO, Masashi , TAKAGAKI, Kozue , NOGAMI, Marina , TSUJI, Riichiro , MEGURO, Hiroyuki , UKEGAWA, Naoya
- 申请人： Toray Industries, Inc.
- 申请人地址： JP Tokyo 103-8666 1-1, Nihonbashi-Muromachi 2-chome, Chuo-ku,
- 代理机构： Kador & Partner Part mbB
- 优先权： JP2020215976 20201225
- 国际公布： WO2022138888 20220630
- 主分类号： C07D215/04
- IPC分类号： C07D215/04 ; A61K31/47 ; A61K31/4709 ; A61K31/496 ; A61K31/5377 ; A61P25/00 ; A61P25/28 ; A61P43/00 ; C07D215/12 ; C07D215/14 ; C07D215/18 ; C07D215/20 ; C07D215/227 ; C07D215/38 ; C07D215/48 ; C07D401/04 ; C07D401/06 ; C07D405/04 ; C07D413/04 ; C07D417/04
摘要：
The purpose of the present invention is to provide a compound having a tetrahydroquinoline skeleton, the compound having inhibitory action against ferroptosis, and exerting therapeutic or preventive effect on diseases, disorders or syndromes related to ferroptosis inhibition, such as multiple sclerosis. The present invention provides a tetrahydroquinoline derivative represented by the following formula or a pharmaceutically acceptable salt thereof.
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