公开(公告)号：EP4269392A1

公开(公告)日：2023-11-01

申请号：EP21911025.1

申请日：2021-12-24

申请人： Toray Industries, Inc.

发明人： ASABA, Ken Nunettsu ,  TAKAHASHI,Takehiro ,  YAMAMOTO, Masashi ,  TAKAGAKI, Kozue ,  NOGAMI, Marina ,  TSUJI, Riichiro ,  MEGURO, Hiroyuki ,  UKEGAWA, Naoya

IPC分类号： C07D215/04 ,  A61K31/47 ,  A61K31/4709 ,  A61K31/496 ,  A61K31/5377 ,  A61P25/00 ,  A61P25/28 ,  A61P43/00 ,  C07D215/12 ,  C07D215/14 ,  C07D215/18 ,  C07D215/20 ,  C07D215/227 ,  C07D215/38 ,  C07D215/48 ,  C07D401/04 ,  C07D401/06 ,  C07D405/04 ,  C07D413/04 ,  C07D417/04

摘要： The purpose of the present invention is to provide a compound having a tetrahydroquinoline skeleton, the compound having inhibitory action against ferroptosis, and exerting therapeutic or preventive effect on diseases, disorders or syndromes related to ferroptosis inhibition, such as multiple sclerosis. The present invention provides a tetrahydroquinoline derivative represented by the following formula or a pharmaceutically acceptable salt thereof.