- 专利标题： METHOD FOR DETERMINING DETERIORATION OF A DISEASE CONDITION OF A PARKINSON S DISEASE PATIENT
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申请号： EP23210551.0申请日： 2018-05-17
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公开(公告)号： EP4306959A3公开(公告)日： 2024-03-27
- 发明人: TSUJI, Hirokazu , ASAHARA, Takashi , NOMOTO, Koji , HIRAYAMA, Masaaki , OHNO, Kinji
- 申请人： Kabushiki Kaisha Yakult Honsha , National University Corporation Tokai National Higher Education and Research System
- 申请人地址： JP Tokyo, 105-8660 1-10-30, Kaigan, Minato-ku,; JP Nagoya-shi, Aichi 464-8601 1, Furo-cho Chikusa-ku
- 代理机构： Wächtershäuser & Hartz Patentanwaltspartnerschaft mbB
- 优先权： JP2017098973 20170518
- 主分类号： C12Q1/06
- IPC分类号： C12Q1/06 ; C12N1/20 ; G01N33/68 ; G01N33/92 ; C12Q1/6851 ; C12Q1/10 ; C12Q1/689 ; G01N33/569
摘要：
The present invention relates to a method for simply diagnosing the progress of disease condition of a Parkinson's disease patient. Provided are a method for determining Parkinson's disease using the number of one or more intestinal bacteria selected from the group consisting of Bifidobacterium, Bacteroides fragilis group, Lactobacillus brevis, and Lactobacillus plantarum subgroup and/or the total number of intestinal bacteria as a marker, and a method for determining Parkinson's disease using the blood LPS level and/or the blood LBP level of a Parkinson's disease patient as an indicator.
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