公开(公告)号：EP4306959A3

公开(公告)日：2024-03-27

申请号：EP23210551.0

申请日：2018-05-17

申请人： Kabushiki Kaisha Yakult Honsha ,  National University Corporation Tokai National Higher Education and Research System

发明人： TSUJI, Hirokazu ,  ASAHARA, Takashi ,  NOMOTO, Koji ,  HIRAYAMA, Masaaki ,  OHNO, Kinji

IPC分类号： C12Q1/06 ,  C12N1/20 ,  G01N33/68 ,  G01N33/92 ,  C12Q1/6851 ,  C12Q1/10 ,  C12Q1/689 ,  G01N33/569

摘要： The present invention relates to a method for simply diagnosing the progress of disease condition of a Parkinson's disease patient. Provided are a method for determining Parkinson's disease using the number of one or more intestinal bacteria selected from the group consisting of Bifidobacterium, Bacteroides fragilis group, Lactobacillus brevis, and Lactobacillus plantarum subgroup and/or the total number of intestinal bacteria as a marker, and a method for determining Parkinson's disease using the blood LPS level and/or the blood LBP level of a Parkinson's disease patient as an indicator.

公开(公告)号：EP4317404A1

公开(公告)日：2024-02-07

申请号：EP22775481.9

申请日：2022-03-18

申请人： Daikin Industries, Ltd.

发明人： KAWAI, Shogo ,  YOSHIMURA, Naomi ,  GOTO, Aoi ,  TAKANO, Wakana ,  OTO, Ryuichiro ,  MAEDA, Shotaro ,  KANETAKE, Mirei ,  NAMIKAWA, Takashi ,  WATANABE, Shiho

IPC分类号： C12M1/34 ,  C12Q1/04 ,  C12Q1/06 ,  G01N21/17 ,  G01N21/88 ,  G01N21/94

摘要： An sure, an inspection system and an inspection method that reduce the time required to inspect environmental microorganisms, are provided. The inspection system inspection system is for inspecting a microorganism or mold that is generated in an indoor environment or a device, and the inspection system includes an imaging unit configured to directly capture a sample collected from the indoor environment or the device; and an output unit configured to inspect the microorganism or the mold in image data captured by the imaging unit, and output an inspection result.

公开(公告)号：EP4308696A1

公开(公告)日：2024-01-24

申请号：EP22716159.3

申请日：2022-03-15

申请人： ApiRays Bioscience AB

发明人： ASALAPURAM RAMACHANDRAN, Pavankumar ,  SANGITH, Nikhil

IPC分类号： C12N9/14 ,  C12Q1/34 ,  C12Q1/00 ,  C12Q1/06 ,  C12Q1/6869

公开(公告)号：EP4303311A2

公开(公告)日：2024-01-10

申请号：EP23195254.0

申请日：2018-09-17

申请人： Phase Scientific International, Ltd.

发明人： CHIU, Yin, To

IPC分类号： C12Q1/06

摘要： The present invention relates to methods of using aqueous two-phase system (ATPS) for the isolation, concentration and/or purification of short nucleic acid fragment having about or less than 250 base pairs (bp). In one embodiment, the present invention provides a composition and kit for the purification of short nucleic acid fragments having about or less than 250 base pairs from nucleic acid-containing biological materials. In another embodiment, the present invention provides uses of certain salts and/or polymers in a two-phase system for the purification of short nucleic acid fragments having about or less than 250 base pairs from nucleic acid containing biological materials.

公开(公告)号：EP4286526A1

公开(公告)日：2023-12-06

申请号：EP22746043.3

申请日：2022-01-28

申请人： Anicom Holdings, Inc.

发明人： MATSUMOTO Kengo ,  SUMI Hiroshi ,  TAKAHASHI Hiroyuki ,  HORIE Ryo

IPC分类号： C12Q1/06 ,  C12Q1/6869 ,  G01N33/48 ,  G06Q50/10

摘要： An object of the invention is to provide a method for predicting and determining obesity in an animal, which is a method for predicting obesity in an animal, including a measurement step of measuring the number of bacterial species belonging to one or more families selected from the group consisting of Streptococcaceae, Ruminococcaceae, Bifidobacteriaceae, Enterococcaceae, Erysipelotrichaceae, Coriobacteriaceae, Prevotellaceae, Coprobacillaceae, and Paraprevotellaceae that are present in the body of the animal or in a sample isolated from the animal.

公开(公告)号：EP3740585B1

公开(公告)日：2023-09-27

申请号：EP19741441.0

申请日：2019-01-16

发明人： GLUKHMAN, Vladimir

IPC分类号： C12Q1/04 ,  C12Q1/06 ,  G01N33/569 ,  G01N33/58 ,  C12M1/34 ,  G01N21/64 ,  C12Q1/10

公开(公告)号：EP4234710A2

公开(公告)日：2023-08-30

申请号：EP23175492.0

申请日：2018-03-28

申请人： Phase Scientific International, Ltd.

发明人： CHIU, Yin, To

IPC分类号： C12Q1/06

摘要： The present invention relates to a method for improving the detection and diagnosis targeting biomarkers using an aqueous two-phase system (ATPS). In one embodiment, the present invention provides a method for improving a diagnostic procedure involving the detection or quantification of one or more biomarkers in liquid biopsy, the method comprises contacting a porous material embedded with ATPS components with a liquid biopsy containing the biomarkers, purifying and concentrating the target biomarkers, and providing a product comprising the target biomarkers for performing the diagnostic procedure.

公开(公告)号：EP4200436A1

公开(公告)日：2023-06-28

申请号：EP21769857.0

申请日：2021-08-20

申请人： Ancera, Inc.

发明人： GANESAN, Arjun ,  VOYTA, John C.

IPC分类号： C12Q1/06 ,  C40B70/00

公开(公告)号：EP4151744A1

公开(公告)日：2023-03-22

申请号：EP20935377.0

申请日：2020-05-12

申请人： HITACHI HIGH-TECH CORPORATION

发明人： SUGIYAMA Kiyotaka ,  FUJITA Hiroko

IPC分类号： C12Q1/06 ,  G01N33/48

摘要： The present invention provides a technique for estimating a bacterial concentration from a sample in which bacteria and impurities are mixed, and adjusting the bacterial concentration in the sample to a desired value. An automatic analyzer according to the present invention introduces a substance that destroys impurities into a sample in which bacteria and the impurities are mixed, separates the destroyed impurities and the bacteria, and then takes out the bacteria by a filter, and estimates the concentration of bacteria in the sample according to correspondence data between the amount of impurities remaining on the filter and the concentration of bacteria in the sample. .

公开(公告)号：EP4146009A1

公开(公告)日：2023-03-15

申请号：EP21800903.3

申请日：2021-04-28

申请人： Wm. Wrigley Jr. Company

发明人： PHILLIPS, David R. ,  LIU, Jingping ,  DODDS, Michael W.

IPC分类号： A23G4/08 ,  C12Q1/06 ,  C12Q1/6806