- 专利标题： DESIGN OF BACTERIOPHAGE-BASED ARTIFICIAL VIRUSES FOR HUMAN GENOME REMODELING
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申请号： EP24155130.8申请日： 2021-07-21
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公开(公告)号： EP4371564A3公开(公告)日： 2024-08-21
- 发明人: RAO, Venigalla B. , ZHU, Jingen
- 申请人： THE CATHOLIC UNIVERSITY OF AMERICA
- 申请人地址： US Washington, DC 20064 620 Michigan Avenue, N.E.
- 专利权人： THE CATHOLIC UNIVERSITY OF AMERICA
- 当前专利权人： THE CATHOLIC UNIVERSITY OF AMERICA
- 当前专利权人地址： US Washington, DC 20064 620 Michigan Avenue, N.E.
- 代理机构： FRKelly
- 优先权： US 2063058012P 2020.07.29
- 分案原申请号： 21850710.1 2021.07.21
- 主分类号： A61K31/7088
- IPC分类号： A61K31/7088 ; C12N7/00 ; C12N15/10 ; C12N15/86
摘要：
Described is an "artificial virus" (AV) programmed with biomolecules that can enter human cells and carry out precise human genome modification. The AVs comprise: at least one viral vector, such as bacteriophage T4; at least one therapeutic molecule, such as DNA, RNA, protein and their complex; and a lipid coating. Also described is a method of human genome modification, using such an AV, and a method of program such an AV.
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