发明专利
JP2008224686A Apparatus and method for creating and testing pre-formulation, and system therefor
审中-公开
用于创造和测试预配制的装置和方法及其系统
- 专利标题： Apparatus and method for creating and testing pre-formulation, and system therefor
- 专利标题（中）： 用于创造和测试预配制的装置和方法及其系统
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申请号： JP2008140198申请日： 2008-05-28
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公开(公告)号： JP2008224686A公开(公告)日： 2008-09-25
- 发明人: CARLSON ERIC D , CONG PEIJUN , CHANDLER WILLIAM H JR , CHAU HENRY K , DANIELSON EARL , DESROSIERS PETER J , DOOLAN ROBERT D , WU LUPING
- 申请人： Symyx Technologies Inc , サイミックス テクノロジーズ, インコーポレイテッド
- 专利权人： Symyx Technologies Inc,サイミックス テクノロジーズ, インコーポレイテッド
- 当前专利权人： Symyx Technologies Inc,サイミックス テクノロジーズ， インコーポレイテッド
- 优先权： US31133201 2001-08-10
- 主分类号： G01N21/64
- IPC分类号： G01N21/64 ; G01N33/50 ; B01J19/00 ; B01L3/00 ; B01L3/06 ; B01L7/00 ; C07B61/00 ; C07D209/20 ; C07D293/00 ; C40B40/10 ; C40B60/08 ; C40B60/14 ; G01N5/04 ; G01N13/00 ; G01N21/23 ; G01N21/27 ; G01N21/33 ; G01N21/35 ; G01N21/47 ; G01N21/65 ; G01N21/78 ; G01N24/08 ; G01N25/04 ; G01N30/88 ; G01N33/15 ; G01N33/483 ; G01N33/53 ; G01N33/543 ; G01N35/02 ; G01N37/00
摘要：
PROBLEM TO BE SOLVED: To provide a methods, an apparatus, and a system for performing a high-throughput preparation and a screening of salts and polymorphs of drug candidates. SOLUTION: The method is directed toward enhancing the pre-formulation discovery process used for a drug development. In particular, processes of determining suitable salts and processes of discovering substantially every polymorph that can form from a particular drug candidate are provided. The processes are performed using several apparatuses that are specifically configured to carry-out various steps in a high-throughput characterization process. One such apparatus is configured for synthesizing a plurality of library members from, for example, a library model generated by a computer system. COPYRIGHT: (C)2008,JPO&INPIT
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