发明授权
- 专利标题： Anti-vasculature and anti-tubulin combretastatin analogs for treatment of cancer
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申请号： US15129785申请日： 2015-03-26
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公开(公告)号： US10017475B2公开(公告)日： 2018-07-10
- 发明人: Guangdi Wang , Shilong Zheng , Qiu Zhong , Qiang Zhang
- 申请人： XAVIER UNIVERSITY OF LOUISIANA
- 申请人地址： US LA New Orleans
- 专利权人： XAVIER UNIVERSITY OF LOUSIANA
- 当前专利权人： XAVIER UNIVERSITY OF LOUSIANA
- 当前专利权人地址： US LA New Orleans
- 代理机构： McBee Moore Woodward & Vanik IP, LLC
- 代理商 Susan McBee; Chester Moore
- 国际申请： PCT/US2015/022624 WO 20150326
- 国际公布： WO2015/153252 WO 20151008
- 主分类号： A61K31/4418
- IPC分类号： A61K31/4418 ; C07D213/61 ; A61K45/06 ; C07D213/30 ; A61K31/4425
摘要：
Combretastatins analog compounds and their pharmaceutically acceptable salts are presented, as well as pharmaceutical compositions comprising the combretastatin analog compounds and uses of the combretastatin analog compounds, either alone or in combination with at least one additional therapeutic agent, in the treatment of cancer, and in particular cancer presenting as metastatic tumors.
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