- 专利标题: Albumin binding antibodies and binding fragments thereof
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申请号: US15795874申请日: 2017-10-27
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公开(公告)号: US10023631B2公开(公告)日: 2018-07-17
- 发明人: Ralph Adams , Pallavi Bhatta , Sam Philip Heywood , David Paul Humphreys
- 申请人: UCB Biopharma SPRL
- 申请人地址: BE Brussels
- 专利权人: UCB Biopharma SPRL
- 当前专利权人: UCB Biopharma SPRL
- 当前专利权人地址: BE Brussels
- 代理机构: Saul Ewing Arnstein & Lehr LLP
- 主分类号: C07K16/18
- IPC分类号: C07K16/18 ; C07K16/28
摘要:
A serum albumin binding antibody or fragment thereof comprising a heavy chain variable domain having the sequence given in SEQ ID NO: 1 or SEQ ID NO:2 and/or comprising a light chain variable domain having the sequence given in SEQ ID NO:3 or SEQ ID NO:4, in particular comprising a heavy chain variable domain and a light chain variable domain having the sequence given in SEQ ID NO: 1 and SEQ ID NO:3 or a heavy chain variable domain and a light chain variable domain having the sequence given in SEQ ID NO: 2 and SEQ ID NO:4. The disclosure also extends to polynucleotides encoding the antibodies or fragments, vectors comprising same and host cells capable of expressing the polynucleotides. The disclosure further includes pharmaceutical compositions comprising the antibodies or fragments and therapeutic used of any one of the same.
公开/授权文献
- US20180134774A1 ALBUMIN BINDING ANTIBODIES AND BINDING FRAGMENTS THEREOF 公开/授权日:2018-05-17
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