Invention Grant
- Patent Title: Anti-sigmas for programmable transcriptional regulation
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Application No.: US14388030Application Date: 2013-03-15
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Publication No.: US10030320B2Publication Date: 2018-07-24
- Inventor: Virgil A. Rhodius , Christopher Voigt , Carol A. Gross
- Applicant: Massachusetts Institute of Technology , The Regents of the University of California
- Applicant Address: US MA Cambridge US CA Oakland
- Assignee: Massachusetts Institute of Technology,The Regents of the University of California
- Current Assignee: Massachusetts Institute of Technology,The Regents of the University of California
- Current Assignee Address: US MA Cambridge US CA Oakland
- Agency: Wolf, Greenfield & Sacks, P.C.
- International Application: PCT/US2013/032145 WO 20130315
- International Announcement: WO2013/148321 WO 20131003
- Main IPC: C12N15/79
- IPC: C12N15/79 ; C40B30/02 ; C07K14/195 ; C12N15/63 ; G06N3/12 ; B82Y10/00
Abstract:
The invention relates to anti-sigma factors (“anti-sigmas”) that bind to sigma factors and block activation of transcription. Anti-sigmas and their cognate sigma factors provide a highly effective mechanism for regulating gene expression in genetic circuits.
Public/Granted literature
- US20150051112A1 ANTI-SIGMAS FOR PROGRAMMABLE TRANSCRIPTIONAL REGULATION Public/Granted day:2015-02-19
Information query
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