Invention Grant
- Patent Title: Hydrochloride salt form for EZH2 inhibition
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Application No.: US15029848Application Date: 2014-10-15
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Publication No.: US10040782B2Publication Date: 2018-08-07
- Inventor: Kevin W. Kuntz , Hyeong-wook Choi , Steven Mathieu , Kristen Sanders , Arani Chanda
- Applicant: Epizyme, Inc. , Eisai R&D Management Co., Ltd.
- Applicant Address: US MA Cambridge JP Bunkyo-ku, Tokyo
- Assignee: Epizyme, Inc.,Eisai R&D Management Co., Ltd.
- Current Assignee: Epizyme, Inc.,Eisai R&D Management Co., Ltd.
- Current Assignee Address: US MA Cambridge JP Bunkyo-ku, Tokyo
- Agency: Cooley LLP
- Agent Heidi A. Erlacher; Christine C. Pemberton
- International Application: PCT/US2014/060724 WO 20141015
- International Announcement: WO2015/057859 WO 20150423
- Main IPC: C07D405/12
- IPC: C07D405/12 ; A61K31/5377 ; C07D413/12
Abstract:
Provided herein are novel solid forms of N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-5-(ethyl(tetrahydro-2H-pyran-4-yl)amino)-4-methyl-4′-(morpholinomethyl)-[1,1′-biphenyl]-3-carboxamide hydrochloride, and related compositions and methods.
Public/Granted literature
- US20160237068A1 HYDROCHLORIDE SALT FORM FOR EZH2 INHIBITION Public/Granted day:2016-08-18
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