Invention Grant
- Patent Title: Nucleic acid-encapsulating polymer micelle complex and method for producing same
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Application No.: US14909162Application Date: 2014-08-05
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Publication No.: US10046065B2Publication Date: 2018-08-14
- Inventor: Kazunori Kataoka , Kensuke Osada , Theofilus Agrios Tockary
- Applicant: JAPAN SCIENCE AND TECHNOLOGY AGENCY
- Applicant Address: JP Saitama
- Assignee: Japan Science and Technology Agency
- Current Assignee: Japan Science and Technology Agency
- Current Assignee Address: JP Saitama
- Agency: Amster, Rothstein & Ebenstein LLP
- Priority: JP2013-163106 20130806
- International Application: PCT/JP2014/070567 WO 20140805
- International Announcement: WO2015/020026 WO 20150212
- Main IPC: B01L3/00
- IPC: B01L3/00 ; C12Q1/04 ; C12Q1/68 ; A61K48/00 ; A61K47/34 ; A61K9/00 ; A61K9/107 ; C12N15/88 ; A61K31/711 ; A61K31/713
Abstract:
A nucleic acid-encapsulating polymer micelle complex is formed of a block copolymer containing an uncharged hydrophilic polymer chain block and a cationic polymer chain block; and two single-stranded DNA molecules having mutually complementary base sequences of 1000 or more bases in length, double-stranded DNA of 1000 or more base pairs in length in which at least a part of a double helix structure is dissociated and forms a single-stranded structure, or one single-stranded DNA molecule of 1000 or more bases in length.
Public/Granted literature
- US20160184457A1 NUCLEIC ACID-ENCAPSULATING POLYMER MICELLE COMPLEX AND METHOD FOR PRODUCING SAME Public/Granted day:2016-06-30
Information query
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