- 专利标题： Applications of the protein muNS and the derivates thereof
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申请号： US13578556申请日： 2011-02-11
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公开(公告)号： US10059745B2公开(公告)日： 2018-08-28
- 发明人: Alberto Brandariz Nunez , Rebeca Menaya Vargas , Francisco Javier Benavente Martinez , Jose Manuel Martinez Costas
- 申请人： Alberto Brandariz Nunez , Rebeca Menaya Vargas , Francisco Javier Benavente Martinez , Jose Manuel Martinez Costas
- 申请人地址： ES A Coruna
- 专利权人： UNIVERSIDADE DE SANTIAGO DE COMPOSTELA
- 当前专利权人： UNIVERSIDADE DE SANTIAGO DE COMPOSTELA
- 当前专利权人地址： ES A Coruna
- 代理机构： Hultquist, PLLC
- 代理商 Steven J. Hultquist
- 优先权： ES201030204 20100212
- 国际申请： PCT/ES2011/070092 WO 20110211
- 国际公布： WO2011/098652 WO 20110818
- 主分类号： A61K39/15
- IPC分类号： A61K39/15 ; C07K14/005 ; A61K38/00
摘要：
The invention is based on the identification of the minimum region of the avian Orthoreovirus muNS protein which is capable of forming inclusions as well as on the identification of specific regions of the muNS protein showing capacity to associate with the inclusions formed by muNS. The identification of said regions allows developing methods for purifying recombinant polypeptides as well as methods for detecting the interaction between two polypeptides of interest.
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