- 专利标题： Method for producing artificial skin model, and artificial skin model
-
申请号： US14008348申请日： 2012-03-29
-
公开(公告)号： US10073085B2公开(公告)日： 2018-09-11
- 发明人: Mitsuru Akashi , Michiya Matsusaki , Takeshi Sakura , Koji Hashimoto , Yuji Shirakata , Satoshi Hirakawa
- 申请人： Mitsuru Akashi , Michiya Matsusaki , Takeshi Sakura , Koji Hashimoto , Yuji Shirakata , Satoshi Hirakawa
- 申请人地址： JP Osaka JP Tokyo
- 专利权人： Osaka University,Toray Industries, Inc.
- 当前专利权人： Osaka University,Toray Industries, Inc.
- 当前专利权人地址： JP Osaka JP Tokyo
- 代理机构： Hamre, Schumann, Mueller & Larson, P.C.
- 优先权： JP2011-072207 20110329
- 国际申请： PCT/JP2012/058329 WO 20120329
- 国际公布： WO2012/133629 WO 20121004
- 主分类号： G01N33/50
- IPC分类号： G01N33/50 ; C12N5/071
摘要：
Provided is a novel method capable of producing an artificial skin model. A method for producing an artificial skin model includes: providing coated cells (1), each of which is obtained by covering the surface of a cell (3) with a coating film (2) containing an extracellular matrix component; forming a dermis tissue layer (7), in which the coated cells (1) are laminated, by culturing the coated cells (1); and forming an epidermis layer (12) by arranging epidermis cells (8) on the dermis tissue layer (7).