- 专利标题: Prenatal paternity testing using maternal blood, free floating fetal DNA and SNP genotyping
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申请号: US13335043申请日: 2011-12-22
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公开(公告)号: US10113196B2公开(公告)日: 2018-10-30
- 发明人: Allison Ryan , Styrmir Sigurjonsson , Milena Banjevic , George Gemelos , Matthew Hill , Johan Baner , Matthew Rabinowitz , Zachary Demko
- 申请人: Allison Ryan , Styrmir Sigurjonsson , Milena Banjevic , George Gemelos , Matthew Hill , Johan Baner , Matthew Rabinowitz , Zachary Demko
- 申请人地址: US CA San Carlos
- 专利权人: Natera, Inc.
- 当前专利权人: Natera, Inc.
- 当前专利权人地址: US CA San Carlos
- 主分类号: C12Q1/6869
- IPC分类号: C12Q1/6869 ; C12Q1/6876 ; G06F19/14
摘要:
Methods for non-invasive prenatal paternity testing are disclosed herein. The method uses genetic measurements made on plasma taken from a pregnant mother, along with genetic measurements of the alleged father, and genetic measurements of the mother, to determine whether or not the alleged father is the biological father of the fetus. This is accomplished by way of an informatics based method that can compare the genetic fingerprint of the fetal DNA found in maternal plasma to the genetic fingerprint of the alleged father.
公开/授权文献
- US20120122701A1 Methods for Non-Invasive Prenatal Paternity Testing 公开/授权日:2012-05-17