Systems, apparatuses, and methods for generating and utilizing sub-pixel sampling patterns on a processor are disclosed. In one embodiment, a processor includes at least multiple execution units and a memory. The processor generates sub-pixel sampling coordinates within each pixel of an image being rendered based on a rotated grid superimposed on the image. The processor also specifies an amount of rotation for the rotated grid. The processor utilizes the sub-pixel sampling coordinates for determining which locations to sample within the image being rendered. The sampling patterns generated based on these techniques enable using more complex and computationally efficient anti-aliasing resolve filters, resulting in higher quality images.