Invention Grant
- Patent Title: 5-aryl-1H-pyrrole-3-carbonitrile and a pharmaceutical product using the same
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Application No.: US14994360Application Date: 2016-01-13
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Publication No.: US10173977B2Publication Date: 2019-01-08
- Inventor: Tomomi Ikemoto , Hideya Mizufune , Toshiaki Nagata , Misayo Sera , Naohiro Fukuda , Takeshi Yamasaki
- Applicant: Takeda Pharmaceutical Company Limited
- Applicant Address: JP Osaka-Shi
- Assignee: Takeda Pharmaceutical Company Limited
- Current Assignee: Takeda Pharmaceutical Company Limited
- Current Assignee Address: JP Osaka-Shi
- Agency: Mintz Levin Cohn Ferris Glovsky and Popeo, P.C.
- Agent David G. Conlin; Joohee Lee
- Priority: JP2009-042975 20090225
- Main IPC: C07D207/337
- IPC: C07D207/337 ; C07D207/333 ; C07D207/34 ; C07D207/36 ; C07D401/12 ; C07D207/30 ; C07D207/48

Abstract:
The present invention provides a production method of a sulfonylpyrrole compound useful as a pharmaceutical product, a production method of an intermediate used for the method, and a novel intermediate. The present invention relates to a method of producing sulfonylpyrrole compound (VIII), which includes reducing compound (III) and hydrolyzing the reduced product to give compound (IV), subjecting compound (IV) to a sulfonylation reaction to give compound (VI), and subjecting compound (VI) to an amination reaction.
Public/Granted literature
- US20180009746A1 PROCESS FOR PRODUCING PYRROLE COMPOUND Public/Granted day:2018-01-11
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