Invention Grant
- Patent Title: Therapeutic compounds and uses thereof
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Application No.: US15482581Application Date: 2017-04-07
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Publication No.: US10206931B2Publication Date: 2019-02-19
- Inventor: F. Anthony Romero , Steven R. Magnuson , Richard Pastor , Vickie Hsiao-Wei Tsui , Jeremy Murray , Terry Crawford , Daniel J. Burdick , Brian K. Albrecht , Alexandre Cote , Alexander M. Taylor , Christopher G. Nasveschuck , Yves LeBlanc , Michael Charles Hewitt , Kwong Wah Lai , Kevin Chen
- Applicant: GENENTECH, INC. , CONSTELLATION PHARMACEUTICALS, INC.
- Applicant Address: US CA South San Francisco US MA Cambridge
- Assignee: GENENTECH, INC.,CONSTELLATION PHARMACEUTICALS, INC.
- Current Assignee: GENENTECH, INC.,CONSTELLATION PHARMACEUTICALS, INC.
- Current Assignee Address: US CA South San Francisco US MA Cambridge
- Agency: Viksnins Harris Padys Malen LLP
- Priority: WOPCT/CN2014/088315 20141010
- Main IPC: A61K31/551
- IPC: A61K31/551 ; C07D243/12 ; C07D403/04 ; C07D403/14 ; A61K31/55 ; C07D223/16 ; C07D267/14 ; C07D401/14 ; C07D401/06 ; C07D401/12 ; C07D403/06 ; C07D405/04 ; C07D405/12 ; C07D413/04 ; C07D413/10 ; C07D243/24 ; C07D471/04 ; C07D495/04 ; A61K45/06 ; A61K31/337 ; A61K31/5513
Abstract:
The present invention relates to compounds of formula (I): and to salts thereof, wherein A has any of the values defined in the specification, and compositions and uses thereof. The compounds are useful as inhibitors of CBP and/or EP300. Also included are pharmaceutical compositions comprising a compound of formula (I) or a pharmaceutically acceptable salt thereof, and methods of using such compounds and salts in the treatment of various CBP and/or EP300-mediated disorders.
Public/Granted literature
- US20170312292A1 THERAPEUTIC COMPOUNDS AND USES THEREOF Public/Granted day:2017-11-02
Information query
