A process of controlling operation in a multi-cylinder engine either during start of operation or low-load conditions is disclosed. The process may include skipping a supply of fuel in a first set of cylinders of the multi-cylinder engine for a pre-defined number of multiple working cycles. The process may further include supplying fuel-air mixture to a second set of cylinders of the multi-cylinder engine for the pre-defined number of multiple working cycles. The process may also include executing combustion of the fuel-air mixture supplied to the second set of cylinders for the pre-defined number of multiple working cycles. In addition the process may include either changing a selection of cylinders included in the first set of cylinders and the second set of cylinders respectively, or switching the supply of fuel, after the pre-defined number of multiple working cycles, from the second set of cylinders to the first set of cylinders.