Invention Grant
- Patent Title: Arylcyclopropylamine based demethylase inhibitors of LSD1 and their medical use
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Application No.: US15623866Application Date: 2017-06-15
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Publication No.: US10233178B2Publication Date: 2019-03-19
- Inventor: Alberto Ortega Muñoz , Matthew Colin Thor Fyfe , Marc Martinell Pedemonte , Iñigo Tirapu Fernandez De La Cuesta , Maria de los Ángeles Estiarte Martinez
- Applicant: Oryzon Genomics S.A.
- Applicant Address: ES Madrid
- Assignee: Oryzon Genomics, S.A.
- Current Assignee: Oryzon Genomics, S.A.
- Current Assignee Address: ES Madrid
- Agency: Finnegan, Henderson, Farabow, Garrett & Dunner, LLP
- Priority: EP10171342 20100729; EP11160728 20110331; EP11160731 20110331; EP11160738 20110331
- Main IPC: A61K31/505
- IPC: A61K31/505 ; A61K31/44 ; C07D417/12 ; A61K31/433 ; A61K31/4245 ; A61K31/422 ; A61K31/506 ; A61K31/4439 ; C07D213/73 ; C07D237/20 ; C07D239/42 ; C07D241/20 ; C07D253/07 ; C07D261/14 ; C07D263/48 ; C07D271/07 ; C07D271/113 ; C07D277/40 ; C07D285/12 ; C07D401/12 ; C07D413/12 ; C07D285/135 ; C07D285/08
Abstract:
The invention relates to (hetero)aryl cyclopropylamine compounds, including particularly the compounds of formula (I) as described and defined herein, and their use in therapy, including, e.g., in the treatment or prevention of cancer, a neurological disease or condition, or a viral infection. Thus, in one specific aspect the invention relates to formulas (II), (III), (IV), (V), (VI), (VII), (VIII), (IX).
Public/Granted literature
- US20180127406A1 ARYLCYCLOPROPYLAMINE BASED DEMETHYLASE INHIBITORS OF LSD1 AND THEIR MEDICAL USE Public/Granted day:2018-05-10
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