Invention Grant
- Patent Title: Biaryl kinase inhibitors
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Application No.: US15763281Application Date: 2016-09-29
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Publication No.: US10246469B2Publication Date: 2019-04-02
- Inventor: Joanne J. Bronson , Ling Chen , Jonathan L. Ditta , Carolyn Diane Dzierba , Prasada Rao Jalagam , Guanglin Luo , John E. Macor , Tarun Kumar Maishal , Susheel Jethanand Nara , Ramkumar Rajamani , Ramesh Kumar Sistla , Soodamani Thangavel
- Applicant: BRISTOL-MYERS SQUIBB COMPANY
- Applicant Address: US NJ Princeton IN Bangalore, Karnataka US NJ Princeton
- Assignee: Bristol-Myers Squibb Company,Syngene International Limited,Bristol-Myers Squibb Company
- Current Assignee: Bristol-Myers Squibb Company,Syngene International Limited,Bristol-Myers Squibb Company
- Current Assignee Address: US NJ Princeton IN Bangalore, Karnataka US NJ Princeton
- Agent Pamela A. Mingo
- Priority: IN3169/DEL/2015 20151001
- International Application: PCT/US2016/054464 WO 20160929
- International Announcement: WO2017/059080 WO 20170406
- Main IPC: C07D401/04
- IPC: C07D401/04 ; C07D401/14 ; C07D403/04 ; C07D403/14 ; C07D237/08 ; C07D239/26 ; C07D213/34 ; A61K31/50 ; A61K31/51 ; A61K31/505 ; A61K31/506 ; A61K31/44 ; A61K31/4427 ; A61P25/28 ; C07D513/04 ; A61P25/18 ; A61P25/16 ; C07D213/74

Abstract:
The present disclosure is directed to biaryl compounds of formula (I) which can inhibit AAK1 (adaptor associated kinase 1), compositions comprising such compounds and their use for treating e.g. pain, Alzheimer's disease, Parkinson's disease and schizophrenia.
Public/Granted literature
- US20190040080A1 BIARYL KINASE INHIBITORS Public/Granted day:2019-02-07
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