公开(公告)号：US20230114740A1

公开(公告)日：2023-04-13

申请号：US18076113

申请日：2022-12-06

申请人： Richard Postrel

发明人： Richard Postrel

IPC分类号： A61K31/436 ,  A61K31/05 ,  A61K31/566 ,  A61K47/44 ,  A61K36/185 ,  A61K31/07 ,  A61K31/51 ,  A61K31/525 ,  A61K31/455 ,  A61K31/197 ,  A61K31/4415 ,  A61K31/4188 ,  A61K31/375 ,  A61K31/519 ,  A61K31/714 ,  A61K31/592 ,  A61K31/593 ,  A61K31/122 ,  A61K33/04 ,  A61K33/00 ,  A61K33/26 ,  A61K33/42 ,  A61K33/30 ,  A61K33/32 ,  A61K33/06 ,  A61P39/00

摘要： The present invention discloses a system and method for increasing the lifespan and quality of life of human beings and other mammals. This discloses methods for preparing and delivering various health and longevity compositions. The compositions of the present invention are selected and designed for the purpose of efficiently delivering health and longevity enhancing therapies through oral supplementation, misting, nasal spray, suppository, etc. An existing compound known to have capacity for life extending potential, rapamycin, is combined with a non-toxic therapeutic anabolic hormone, e.g., DHEA, and cannabidiol (CBD) to enable absorption and effect. These three compounds work together to dramatically improve both the quality of life in aging humans and other mammals as well as extending the life of humans potentially up to 120 healthy years. One preferred embodiment provides a method for continuous low dose supplementation, e.g., incorporated in or with a daily meal. This invention not only resolves the issue of anti-aging of higher life forms, without toxicity, but provides for an improved method for absorption.

公开(公告)号：US20230054630A1

公开(公告)日：2023-02-23

申请号：US17760207

申请日：2021-02-05

申请人： SOCIETE DES PRODUITS NESTLE S.A.

发明人： KURT SEIDENSTICKER ,  COREY FRIESE ,  KATIE COTE ,  CRISTINA CUTRI

IPC分类号： A61K38/39 ,  A61K31/198 ,  A61K31/185 ,  A61K31/375 ,  A61K31/51 ,  A61K31/525 ,  A61K31/455 ,  A61K31/4415 ,  A61K31/519 ,  A61K33/06 ,  A61K33/30 ,  A61K33/04 ,  A61K33/00 ,  A61K31/405 ,  A61K31/197 ,  A23L33/28 ,  A23L33/175 ,  A23L33/16 ,  A23L33/155

摘要： The present invention is directed to improving sleep quality and supporting recovery of joints, ligaments, and tendons with collagen peptides and dietary ingredients that support sleep quality. The supplement composition of the present invention comprises collagen, GABA, L-Theanine, 5-HTP, L-Tryptophan, and Magnesium. The recovery from exercise and physical activity is improved using this combination of components.

公开(公告)号：US20230028626A1

公开(公告)日：2023-01-26

申请号：US17945054

申请日：2022-09-14

申请人： Edgar Lee Hull, JR.

发明人： Edgar Lee Hull, JR.

IPC分类号： A61K38/44 ,  A61K31/4415 ,  A61K31/714 ,  A61K31/519 ,  A61K33/30 ,  A61K31/51 ,  A61K31/122 ,  A61K31/405 ,  A61K31/355 ,  A61K31/455 ,  A61K31/197 ,  A61K33/00 ,  A61K31/198 ,  A61K31/4172 ,  A61K31/525 ,  A61K33/04

摘要： A vitamin for use by kidney patients in Stages 3, 4, 4a, 4b, and 5, who are not on dialysis, comprising administering daily a: low nitrogen diet; low nitrogen protein food comprising magnesium and/or calcium salts of alpha keto acids; and time released vitamin. The vitamin comprises the active ingredients of: Zinc; Selenium; Vitamins B1, B2, B6, B12, B5, E, and K2; Niacin; superoxide dismutase; catalase; glutathione and Folate; and excludes calcium, magnesium, phosphorus, sodium, manganese, fluoride, Vitamin D and K1. The low nitrogen food contains daily up to 300 mg of nitrogen; and at least five alpha keto analogues of magnesium and/or calcium salts of: leucine, isoleucine, methionine (MEMS-II), phenylalanine (PAMS-I), and valine. Methods of making and the chemical structures MEMS-II and the PAMS-I are disclosed. The treatment results in an increase of Glomerular Filtration Rate (GFR), a decrease in blood urea levels, and a decrease in creatinine levels.

公开(公告)号：US11529331B2

公开(公告)日：2022-12-20

申请号：US17303353

申请日：2021-05-27

申请人： Boulder BioScience LLC

发明人： Michael A. Zeligs ,  Irwin C. Jacobs

IPC分类号： A61K31/404 ,  A61P7/02 ,  A61P9/10 ,  A61K9/00 ,  A61K31/122 ,  A61K31/137 ,  A61K31/203 ,  A61K31/23 ,  A61K31/4045 ,  A61K31/41 ,  A61K31/4427 ,  A61K31/451 ,  A61K31/4706 ,  A61K31/51 ,  A61K31/519 ,  A61K31/5377 ,  A61K31/704 ,  A61K38/46 ,  A61K38/48 ,  A61K39/395

摘要： Provided herein are methods of enhancing mechanical thrombectomy during endovascular therapy for acute thrombosis using 3,3′-diindolylmethane.

公开(公告)号：US20220370449A1

公开(公告)日：2022-11-24

申请号：US17818058

申请日：2022-08-08

申请人： GIDD COMMERCIAL USA, INC.

发明人： Juan Raúl MEIXUEIRO-MONTES-DE-OCA

IPC分类号： A61K31/51 ,  A61K31/12 ,  A61K31/4415 ,  A61K31/352 ,  A61K31/7048

摘要： The present invention relates to a physicochemically stable pharmaceutical composition, in a unit dose characterized in that it comprises effective amounts of the active ingredients thiamine (Vitamin B1), pyridoxine (Vitamin B6), a flavonoid such as quercetin and a polyphenol such as curcumin, or their pharmaceutically acceptable salts in combination with pharmaceutically acceptable excipients, for the prevention of the formation and/or trapping of advanced glycation end products (glyoxal, methylglyoxal, N-carboxymethyl-lysine, N-carboxyethyl-lysine, pyrraline, pentosidine, lysine dimer, etc.), which can be used in the treatment and/or prevention of complications of diabetes mellitus (diabetic neuropathy, nephropathy and retinopathy).
The pharmaceutical composition of the invention is presented orally, preferably in capsule, pill or sachet for oral administration.

公开(公告)号：US11484544B2

公开(公告)日：2022-11-01

申请号：US16763392

申请日：2018-05-30

申请人： Mi Gyoung Yang

发明人： Mi Gyoung Yang

IPC分类号： A61K38/18 ,  A61K38/17 ,  A61K8/44 ,  A61K8/60 ,  A61P17/14 ,  A61Q5/02 ,  A61Q5/08 ,  A61Q5/12 ,  A61Q7/02 ,  A61Q7/00 ,  A61K31/7076 ,  A61K8/34 ,  A61K8/36 ,  A61K8/49 ,  A61K8/64 ,  A61K8/67 ,  A61K31/047 ,  A61K31/198 ,  A61K31/20 ,  A61K31/201 ,  A61K31/202 ,  A61K31/375 ,  A61K31/401 ,  A61K31/405 ,  A61K31/4172 ,  A61K31/4188 ,  A61K31/4415 ,  A61K31/455 ,  A61K31/51 ,  A61K31/519 ,  A61K31/52 ,  A61K31/525 ,  A61K31/714

摘要： A pharmaceutical composition or a cosmetic composition for treating hair loss, or promoting hair growth is described. The composition according to the present invention exhibits an excellent effect of treating hair loss and promoting hair growth, and can be safely used regardless of sex and age.

公开(公告)号：US11446338B2

公开(公告)日：2022-09-20

申请号：US16954854

申请日：2018-05-04

申请人： Boris Farber ,  Sof'ya Farber

发明人： Boris Farber ,  Sof'ya Farber ,  Artur Viktorovich Martynov

IPC分类号： A61K35/742 ,  A61K45/06 ,  A61K31/196 ,  A61K31/205 ,  A61K36/064 ,  A61K36/484 ,  A61K36/28 ,  A61K35/748 ,  A61K36/48 ,  A61K31/714 ,  A61K31/525 ,  A61K31/51 ,  A61K31/519 ,  A61K31/7048 ,  A61K31/198 ,  A61K31/145 ,  A61K36/66 ,  A61K31/472 ,  A61K8/99 ,  A61K8/44 ,  A61K8/9789 ,  A61K8/9728 ,  A61K8/67 ,  A61K8/60 ,  A61K8/46 ,  A61K8/49 ,  A61Q11/00 ,  A23L33/135 ,  A23L33/105 ,  A23L33/175 ,  A23L33/15 ,  A23L33/00

摘要： Field of application: the invention relates to biotechnology, can be used in the food industry, medicine and cosmetology in the prevention and/or treatment of diseases associated with immunodeficiencies and respiratory viral infections.
The proposed food, cosmetic and pharmaceutical composition with an immunomodulating and protective antiviral effect additionally has the ability to completely prevent infection by a number of viruses, including influenza, rotavirus and coronavirus, as well as stimulate the immune system more than individual probiotics.

公开(公告)号：US20220279831A1

公开(公告)日：2022-09-08

申请号：US17750969

申请日：2022-05-23

申请人： Exeltis France

发明人： Philippe PERRIN ,  Guillaume HERRY

IPC分类号： A23L33/16 ,  A23L33/12 ,  A23L33/15 ,  A23L33/00 ,  A23L33/155 ,  A61K9/48 ,  A61K31/015 ,  A61K31/202 ,  A61K31/355 ,  A61K31/375 ,  A61K31/4415 ,  A61K31/455 ,  A61K31/51 ,  A61K31/519 ,  A61K31/525 ,  A61K31/593 ,  A61K31/714 ,  A61K31/715 ,  A61K33/08 ,  A61K33/18 ,  A61K33/26 ,  A61K33/30 ,  A61K33/34 ,  A61K36/02

摘要： A method for improving a nutritional status in a prenatal, pregnant or breastfeeding patient. The method includes providing a pharmaceutical composition in a single oral dosage form for administration to a prenatal, pregnant or breastfeeding patient. The pharmaceutical composition consists of vitamin D, iodine, vitamin B1, vitamin B6, vitamin B12, vitamin B2, vitamin B9, vitamin B3, vitamin E, vitamin A, vitamin C, iron, zinc, copper, magnesium, omega-3 fatty acids and one or more pharmaceutically acceptable carriers. The method further includes providing a daily dosage regimen for administering the single oral dosage form to the patient to improve a nutritional status in the patient.

公开(公告)号：US20220249647A1

公开(公告)日：2022-08-11

申请号：US17596401

申请日：2020-06-18

申请人： Janssen Sciences Ireland Unlimited Company

发明人： Helen HORTON ,  Jan Martin BERKE ,  Frederik PAUWELS

IPC分类号： A61K39/12 ,  A61K31/5377 ,  A61K31/51 ,  A61K45/06 ,  A61P31/20 ,  C12N7/00

摘要： Therapeutic combinations of hepatitis B virus (HBV) vaccines and capsid assembly modulators are described. Methods of inducing an immune response against HBV or treating an HBV-induced disease, particularly in individuals having chronic HBV infection, using the disclosed therapeutic combinations are also described.

公开(公告)号：US20220233651A1

公开(公告)日：2022-07-28

申请号：US17595874

申请日：2020-06-03

申请人： SOCIÉTÉ DES PRODUITS NESTLÉ S.A.

发明人： KURT SEIDENSTICKER ,  MATT APORTA ,  COREY FRIESE ,  ANGELA SKUBAL

IPC分类号： A61K38/39 ,  A61K31/185 ,  A61K31/375 ,  A61K31/51 ,  A61K31/525 ,  A61K31/455 ,  A61K31/675 ,  A61K31/519 ,  A61K33/06 ,  A61K33/30 ,  A61K33/04 ,  A61K33/00 ,  A61K9/14 ,  A23L33/175 ,  A23L33/155 ,  A23L33/00 ,  A61K31/198

摘要： The present invention is directed to a method of replacing collagen broken down during physical activity using a novel dietary supplement. The supplement composition of the present invention comprises collagen, glutamine, taurine, and, optionally, the nine essential amino acids. The uptake of collagen is enhanced using this combination of components to levels substantially near the pre-workout levels.