Invention Grant
![Substituted pyrazolo[1,5-a]pyrimidine compounds as Trk kinase inhibitors](/docs/US/2019-04-09/US10251889B2/abs.jpg.600x600.jpg)
- Patent Title: Substituted pyrazolo[1,5-a]pyrimidine compounds as Trk kinase inhibitors
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Application No.: US15724601Application Date: 2017-10-04
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Publication No.: US10251889B2Publication Date: 2019-04-09
- Inventor: Shelley Allen , Steven W. Andrews , Kevin Ronald Condroski , Julia Haas , Lily Huang , Yutong Jiang , Timothy Kercher , Jeongbeob Seo
- Applicant: Array BioPharma, Inc.
- Applicant Address: US CO Boulder
- Assignee: Array BioPharm Inc.
- Current Assignee: Array BioPharm Inc.
- Current Assignee Address: US CO Boulder
- Agency: Fish & Richardson P.C.
- Main IPC: C07D487/04
- IPC: C07D487/04 ; A61K31/519 ; C07D519/00 ; C07D453/02 ; C07D471/22 ; C07D498/22 ; A61K31/5377
![Substituted pyrazolo[1,5-a]pyrimidine compounds as Trk kinase inhibitors](/abs-image/US/2019/04/09/US10251889B2/abs.jpg.150x150.jpg)
Abstract:
Compounds of Formula I: and salts thereof in which R1, R2, R3, R4, X, Y and n have the meanings given in the specification, are inhibitors of Trk kinases and are useful in the treatment of diseases which can be treated with a Trk kinase inhibitor such as pain, cancer, inflammation, neurodegenerative diseases and certain infectious diseases.
Public/Granted literature
- US20180263984A1 SUBSTITUTED PYRAZOLO[1,5-a]PYRIMIDINE COMPOUNDS AS TRK KINASE INHIBITORS Public/Granted day:2018-09-20
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