Invention Grant
- Patent Title: Aryl sultam derivatives as RORc modulators
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Application No.: US15847407Application Date: 2017-12-19
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Publication No.: US10259808B2Publication Date: 2019-04-16
- Inventor: Benjamin Fauber , Emanuela Gancia , Tammy Ladduwahetty , David Vesey , Paul Winship , Olivier Rene
- Applicant: Genentech, Inc.
- Applicant Address: US CA South San Francisco
- Assignee: Genentech, Inc.
- Current Assignee: Genentech, Inc.
- Current Assignee Address: US CA South San Francisco
- Agent Robert C. Hall
- Main IPC: C07D417/12
- IPC: C07D417/12 ; C07D417/14 ; C07D417/10 ; A61K31/541 ; A61P19/02 ; A61P17/06

Abstract:
Compounds of the formula I: or pharmaceutically acceptable salts thereof, wherein m, n, p, q, r, X1, X2, X3, X4, Y, Z, A, Het, R1, R2, R3, R4, R5 R6, R7, R8, R9, R10, R11, R12 and R13 are as defined herein. Also disclosed are methods of making the compounds and using the compounds for treatment of inflammatory diseases such as arthritis, muscular sclerosis and psoriasis.
Public/Granted literature
- US20180105516A1 ARYL SULTAM DERIVATIVES AS RORc MODULATORS Public/Granted day:2018-04-19
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