-
公开(公告)号：US20140031330A1
公开(公告)日：2014-01-30
申请号：US13939962
申请日：2013-07-11
Applicant: Genentech, Inc.
Inventor： Monique Bodil van Niel , Benjamin Fauber , Simon Gaines , Alberto Gobbi , Olivier Rene , David Vesey , Stuart Ward
IPC: C07D487/04 , C07D417/12 , C07D471/04 , C07D295/185
CPC classification number: C07D295/185 , C07D275/02 , C07D279/02 , C07D281/02 , C07D291/02 , C07D417/10 , C07D417/12 , C07D417/14 , C07D451/14 , C07D471/04 , C07D471/08 , C07D471/10 , C07D487/04 , C07D487/08 , C07D491/10 , C07D498/10 , C07D513/10 , C07D515/12
Abstract: Compounds of the formula I: or pharmaceutically acceptable salts thereof, wherein m, n, p, q, r, A, W, X1, X2, X3, X4, Y, Z, R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, and R12 are as defined herein. Also disclosed are methods of making the compounds and using the compounds for treatment of inflammatory diseases such as arthritis.
Abstract translation: 式I化合物或其药学上可接受的盐，其中m，n，p，q，r，A，W，X1，X2，X3，X4，Y，Z，R1，R2，R3，R4，R5，R6 ，R7，R8，R9，R10，R11和R12如本文所定义。 还公开了制备化合物和使用该化合物治疗炎性疾病如关节炎的方法。
-
公开(公告)号：US09751873B2
公开(公告)日：2017-09-05
申请号：US15047523
申请日：2016-02-18
Applicant: Genentech, Inc.
Inventor： Benjamin Fauber , Alberto Gobbi , Olivier Rene , Monique Bodil van Niel , Emanuela Gancia , Simon Gaines , Tammy Ladduwahetty , David Vesey , Stuart Ward , Paul Winship
IPC: C07D417/14 , C07D417/10 , C07D279/02 , C07D417/12 , C07D491/107 , C07D491/113 , C07D487/08
CPC classification number: C07D417/10 , C07D279/02 , C07D417/12 , C07D417/14 , C07D487/08 , C07D491/107 , C07D491/113
Abstract: Compounds of the formula I: or pharmaceutically acceptable salts thereof, wherein m, n, p, q, r, A, W, X1, X2, X3, X4, Y, Z, R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11 and R12 are as defined herein. Also disclosed are methods of making the compounds and using the compounds for treatment of inflammatory diseases such as arthritis.
-
公开(公告)号：US20170137393A1
公开(公告)日：2017-05-18
申请号：US15199447
申请日：2016-06-30
Applicant: Genentech, Inc.
Inventor： Monique Bodil van Niel , Benjamin Fauber , Emanuela Gancia , Simon Gaines , Alberto Gobbi , Christopher Hurley , Tammy Ladduwahetty , Olivier Rene , David Vesey , Stuart Ward , Paul Winship
IPC: C07D279/02 , C07D417/12 , C07D417/10
CPC classification number: C07D279/02 , C07D417/10 , C07D417/12 , C07D417/14 , C07D487/08
Abstract: Compounds of the formula I: or pharmaceutically acceptable salts thereof, wherein m, n, p, q, r, X1, X2, X3, X4, Y, Z, A, R1, R2, R3, R4, R5 R6, R7, R8, R9, R10, R11, R12 and R13 are as defined herein. Also disclosed are methods of making the compounds and using the compounds for treatment of inflammatory diseases such as arthritis, muscular sclerosis and psoriasis.
-
Patent Agency Ranking
公开(公告)号：US09115101B2
公开(公告)日：2015-08-25
申请号：US13939962
申请日：2013-07-11
Applicant: Genentech, Inc.
Inventor： Monique Bodil van Niel , Benjamin Fauber , Simon Gaines , Alberto Gobbi , Olivier Rene , David Vesey , Stuart Ward
IPC: C07D417/10 , C07D417/12 , C07D417/14 , C07D279/02 , C07D281/02 , C07D291/02 , C07D295/185 , C07D491/10 , C07D513/10 , A61K31/541 , A61P19/02 , C07D451/14 , C07D471/04 , C07D471/08 , C07D471/10 , C07D487/04 , C07D487/08 , C07D275/02 , C07D498/10 , C07D515/12
CPC classification number: C07D295/185 , C07D275/02 , C07D279/02 , C07D281/02 , C07D291/02 , C07D417/10 , C07D417/12 , C07D417/14 , C07D451/14 , C07D471/04 , C07D471/08 , C07D471/10 , C07D487/04 , C07D487/08 , C07D491/10 , C07D498/10 , C07D513/10 , C07D515/12
Abstract: Compounds of the formula I: or pharmaceutically acceptable salts thereof, wherein m, n, p, q, r, A, W, X1, X2, X3, X4, Y, Z, R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, and R12 are as defined herein. Also disclosed are methods of making the compounds and using the compounds for treatment of inflammatory diseases such as arthritis.
Abstract translation: 式I化合物或其药学上可接受的盐，其中m，n，p，q，r，A，W，X1，X2，X3，X4，Y，Z，R1，R2，R3，R4，R5，R6 ，R7，R8，R9，R10，R11和R12如本文所定义。 还公开了制备化合物和使用该化合物治疗炎性疾病如关节炎的方法。
-
公开(公告)号：US20150197529A1
公开(公告)日：2015-07-16
申请号：US14593260
申请日：2015-01-09
Applicant: Genentech, Inc.
Inventor： Benjamin Fauber , Alberto Gobbi , Olivier Rene , Monique Bodil van Niel , Emanuela Gancia , Simon Gaines , Tammy Laddywahetty , David Vesey , Stuart Ward , Paul Winship
IPC: C07D491/113 , C07D491/107 , C07D417/12 , C07D417/14 , C07D279/02
CPC classification number: C07D417/10 , C07D279/02 , C07D417/12 , C07D417/14 , C07D487/08 , C07D491/107 , C07D491/113
Abstract: Compounds of the formula I: or pharmaceutically acceptable salts thereof, wherein m, n, p, q, r, A, W, X1, X2, X3, X4, Y, Z, R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11 and R12 are as defined herein. Also disclosed are methods of making the compounds and using the compounds for treatment of inflammatory diseases such as arthritis.
Abstract translation: 式I化合物或其药学上可接受的盐，其中m，n，p，q，r，A，W，X1，X2，X3，X4，Y，Z，R1，R2，R3，R4，R5，R6 ，R7，R8，R9，R10，R11和R12如本文所定义。 还公开了制备化合物和使用该化合物治疗炎性疾病如关节炎的方法。
-
公开(公告)号：US10259808B2
公开(公告)日：2019-04-16
申请号：US15847407
申请日：2017-12-19
Applicant: Genentech, Inc.
Inventor： Benjamin Fauber , Emanuela Gancia , Tammy Ladduwahetty , David Vesey , Paul Winship , Olivier Rene
IPC: C07D417/12 , C07D417/14 , C07D417/10 , A61K31/541 , A61P19/02 , A61P17/06
Abstract: Compounds of the formula I: or pharmaceutically acceptable salts thereof, wherein m, n, p, q, r, X1, X2, X3, X4, Y, Z, A, Het, R1, R2, R3, R4, R5 R6, R7, R8, R9, R10, R11, R12 and R13 are as defined herein. Also disclosed are methods of making the compounds and using the compounds for treatment of inflammatory diseases such as arthritis, muscular sclerosis and psoriasis.
-
公开(公告)号：US10131644B2
公开(公告)日：2018-11-20
申请号：US15199447
申请日：2016-06-30
Applicant: Genentech, Inc.
Inventor： Monique Bodil van Niel , Benjamin Fauber , Emanuela Gancia , Simon Gaines , Alberto Gobbi , Christopher Hurley , Tammy Ladduwahetty , Olivier Rene , David Vesey , Stuart Ward , Paul Winship
IPC: C07D279/02 , C07D417/10 , C07D417/12
Abstract: Compounds of the formula I: or pharmaceutically acceptable salts thereof, wherein m, n, p, q, r, X1, X2, X3, X4, Y, Z, A, R1, R2, R3, R4, R5 R6, R7, R8, R9, R10, R11, R12 and R13 are as defined herein. Also disclosed are methods of making the compounds and using the compounds for treatment of inflammatory diseases such as arthritis, muscular sclerosis and psoriasis.
-
公开(公告)号：US20160168141A1
公开(公告)日：2016-06-16
申请号：US15047523
申请日：2016-02-18
Applicant: Genentech, Inc.
Inventor： Benjamin Fauber , Alberto Gobbi , Olivier Rene , Monique Bodil van Niel , Emanuela Gancia , Simon Gaines , Tammy Ladduwahetty , David Vesey , Stuart Ward , Paul Winship
IPC: C07D417/10
CPC classification number: C07D417/10 , C07D279/02 , C07D417/12 , C07D417/14 , C07D487/08 , C07D491/107 , C07D491/113
Abstract: Compounds of the formula I: or pharmaceutically acceptable salts thereof, wherein m, n, p, q, r, A, W, X1, X2, X3, X4, Y, Z, R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11 and R12 are as defined herein. Also disclosed are methods of making the compounds and using the compounds for treatment of inflammatory diseases such as arthritis.
-
-
-
-
-
-
-
Search Results
8
records
(took 0.022 seconds)
