An example apparatus for random sampling for horizontal noise reduction includes readout circuitry coupled to receive image data from an array of pixels, the readout circuitry including a plurality of sample and hold (S&H) circuits coupled to respective ones of a plurality of bitlines to sample and hold the image data in response to a plurality of S&H control signals, each of the plurality of S&H circuits including an S&H capacitor and an S&H switch. The S&H capacitor samples and holds respective image data, and the S&H switch coupled between a respective bitline and the respective S&H capacitor, and further coupled to receive a respective one of the plurality of S&H control signals to open/close the S&H switch, where each of the plurality of S&H switches are opened to decouple their respective S&H capacitors from the respective bitlines at a different time.