Invention Grant
- Patent Title: Fusarium toxin-cleaving polypeptide variants, additive containing same, use of same, and method for splitting fusarium toxins
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Application No.: US15553218Application Date: 2015-02-24
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Publication No.: US10264807B2Publication Date: 2019-04-23
- Inventor: Markus Aleschko , Corinna Kern , Dieter Moll , Eva Maria Binder , Gerd Schatzmayr
- Applicant: ERBER AKTIENGESELLSCHAFT
- Applicant Address: AT Getzersdorf bei Traismauer
- Assignee: ERBER AKTIENGESELLSCHAFT
- Current Assignee: ERBER AKTIENGESELLSCHAFT
- Current Assignee Address: AT Getzersdorf bei Traismauer
- Agency: Jacobson Holman, PLLC
- International Application: PCT/AT2015/000032 WO 20150224
- International Announcement: WO2016/134387 WO 20160901
- Main IPC: C12N9/18
- IPC: C12N9/18 ; C12N15/55 ; A23K10/14 ; A23K50/30 ; A23K50/60 ; A23K20/147 ; C12N1/21

Abstract:
The invention relates to fusarium toxin-cleaving polypeptide variants of a fusarium toxin carboxyl esterase with the SEQ ID NO:46. Each of the polypeptide variants has an amino acid sequence shortened by 47 amino acids at the N terminus, and the amino acid sequences have at least 70%, preferably 80%, in particular 100%, sequence identity, namely SEQ ID NO:1, to the amino acid sequence portion 48-540 of the SEQ ID NO:46. The invention also relates to isolated polynucleotides which code for the polypeptide variants, to a fusarium toxin-cleaving additive containing at least one polypeptide variant and optionally at least one auxiliary agent, to the use of the polypeptide variants or the additive, and to a method for hydrolytically cleaving at least one fusarium toxin.
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