Invention Grant
- Patent Title: Means and methods for influencing the stability of antibody producing cells
-
Application No.: US15612096Application Date: 2017-06-02
-
Publication No.: US10273454B2Publication Date: 2019-04-30
- Inventor: Hergen Spits , Ferenc A. Scheeren , Tim Beaumont , Sean A. Diehl
- Applicant: ACADEMISCH MEDISCH CENTRUM BIJ DE UNIVERSITEIT VAN AMSTERDAM , AIMM THERAPEUTICS B.V.
- Applicant Address: NL Amsterdam
- Assignee: ACADEMISCH MEDISCH CENTRUM BIJ DE UNIVERSITEIT VAN AMSTERDAM
- Current Assignee: ACADEMISCH MEDISCH CENTRUM BIJ DE UNIVERSITEIT VAN AMSTERDAM
- Current Assignee Address: NL Amsterdam
- Agency: Saul Ewing Arnstein & Lehr LLP
- Agent Gianna J. Arnold
- Priority: WOPCT/NL2005/000848 20051209; EP06076211 20060612
- Main IPC: C12N5/10
- IPC: C12N5/10 ; C12N5/0781 ; C07K16/00
Abstract:
The invention provides a method for influencing the stability of an antibody producing cell, comprising directly or indirectly influencing the amount of BCL6 and/or Blimp 1 expression product within said antibody producing cell. Stable antibody producing cells and cell lines are also provided, as well as methods for producing antibodies using such cells and/or cell lines.
Public/Granted literature
- US20170306293A1 MEANS AND METHODS FOR INFLUENCING THE STABILITY OF ANTIBODY PRODUCING CELLS Public/Granted day:2017-10-26
Information query
