- 专利标题： Treatment of interferon regulatory factor 8 (IRF8) related diseases by inhibition of natural antisense transcript to IRF8
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申请号： US15798999申请日： 2017-10-31
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公开(公告)号： US10280421B2公开(公告)日： 2019-05-07
- 发明人: Joseph Collard , Olga Khorkova Sherman
- 申请人： CuRNA, Inc.
- 申请人地址： US FL Miami
- 专利权人： CuRNA, Inc.
- 当前专利权人： CuRNA, Inc.
- 当前专利权人地址： US FL Miami
- 代理机构： CuRNA
- 代理商 Monte R. Browder
- 主分类号： C12N15/113
- IPC分类号： C12N15/113 ; A61K31/7088 ; C12Q1/68 ; C12Q1/6876
摘要：
The present invention relates to antisense oligonucleotides that modulate the expression of and/or function of Interferon Regulatory Factor 8 (IRF8), in particular, by targeting natural antisense polynucleotides of Interferon Regulatory Factor 8 (IRF8). The invention also relates to the identification of these antisense oligonucleotides and their use in treating diseases and disorders associated with the expression of IRF8.
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