Invention Grant
- Patent Title: Sensitivity and the dynamic range of photometric assays by generating multiple calibration
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Application No.: US15951536Application Date: 2018-04-12
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Publication No.: US10288609B2Publication Date: 2019-05-14
- Inventor: Thorsten Brueckner , Eloisa Lopez-Calle , Norbert Oranth , Josef Roedl
- Applicant: Roche Diagnostics Operations, Inc.
- Applicant Address: US IN Indianapolis
- Assignee: ROCHE DIAGNOSTICS OPERATIONS, INC.
- Current Assignee: ROCHE DIAGNOSTICS OPERATIONS, INC.
- Current Assignee Address: US IN Indianapolis
- Agency: Woodard, Emhardt, Henry, Reeves & Wagner, LLP
- Priority: EP12002952 20120426; EP12196036 20121207
- Main IPC: G01N21/27
- IPC: G01N21/27 ; G01N21/63 ; G01N33/52 ; G06F19/18 ; G01N33/543 ; G16B20/00 ; G01N21/78 ; G01N21/82 ; G01D18/00 ; G01N33/573 ; G01N33/68 ; G01N33/92 ; G16H50/30

Abstract:
A method for determining the amount of a specific analyte by photometric assays, wherein the specific analyte in a sample reacts with an analyte specific reaction partner in a reaction mixture. At least two calibration curves are generated, the first calibration curve recorded at a first wavelength is optimized for low concentrations of the specific analyte thereby maximizing the lower detection limit and, the second calibration curve recorded at a second wavelength is optimized for high concentrations of the specific analyte thereby maximizing the upper detection limit. The optimized lower detection limit and the optimized upper detection limit results in an extended dynamic range.
Public/Granted literature
- US20180231544A1 SENSITIVITY AND THE DYNAMIC RANGE OF PHOTOMETRIC ASSAYS BY GENERATING MULTIPLE CALIBRATION Public/Granted day:2018-08-16
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