Multiple wireless devices in a network perform full duplex communication in which the transmission path and receiving path are spatially separated to allow simultaneous transmission and receiving. The wireless devices can either be controlled using a centralized, or point, coordination function or a distributed coordination function. A full-duplex wireless device senses the medium during transmission by itself and selectively continues the transmission when a signal is sensed on the medium. A full-duplex wireless device measures signal being transmitted by its transmitter and estimates parameters that can be used to cancel the contribution of the locally transmitted signal to the locally received signal concurrently being received during the transmission. The transmit antenna and the receive antenna of a full-duplex wireless device can be configured to be spatially isolated from each other to minimize interference between the antenna functions.