Example methods, systems, and apparatus to provide selective memory error protection and memory access granularity are disclosed herein. An example system includes a memory controller to determine a selected memory mode based on a request. The memory mode indicates that a memory page is to store a corresponding type of error protection information and is to store data for retrieval using a corresponding access granularity. The memory controller is to store the data and the error protection information in the memory page for retrieval using the error protection information and the access granularity.