Invention Grant
- Patent Title: G protein-coupled receptor kinase inhibitors and methods for use of the same
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Application No.: US15738606Application Date: 2016-06-27
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Publication No.: US10329283B2Publication Date: 2019-06-25
- Inventor: Scott D. Larsen , John J. G. Tesmer , Helen Waldschmidt , Kristoff Homan , Michael William Wilson
- Applicant: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
- Applicant Address: US MI Ann Arbor
- Assignee: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
- Current Assignee: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
- Current Assignee Address: US MI Ann Arbor
- Agency: Marshall, Gerstein & Borun LLP
- International Application: PCT/US2016/039526 WO 20160627
- International Announcement: WO2016/210403 WO 20161229
- Main IPC: C07D405/14
- IPC: C07D405/14 ; C07D401/14 ; C07D401/12 ; C07D405/12 ; A61P9/00 ; A61P9/12
Abstract:
Disclosed herein are novel GRK inhibitors and methods for their use in treating or preventing heart disease, such as cardiac failure, cardiac hypertrophy, and hypertension. In particular, disclosed herein are compounds of Formula (I) and pharmaceutically acceptable salt thereof, wherein the substituents are as described.
Public/Granted literature
- US20180186779A1 G PROTEIN-COUPLED RECEPTOR KINASE INHIBITORS AND METHODS FOR USE OF THE SAME Public/Granted day:2018-07-05
Information query
