Invention Grant
- Patent Title: Dual-action compounds targeting adenosine A2A receptor and adenosine transporter for prevention and treatment of neurodegenerative diseases
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Application No.: US14849782Application Date: 2015-09-10
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Publication No.: US10342818B2Publication Date: 2019-07-09
- Inventor: Yun-Lian Lin , Yijuang Chern , Jim-Min Fang , Jung-Hsing Lin , Nai-Kuei Huang
- Applicant: Academia Sinica
- Applicant Address: TW Taipei
- Assignee: ACADEMIA SINICA
- Current Assignee: ACADEMIA SINICA
- Current Assignee Address: TW Taipei
- Agency: Birch, Stewart, Kolasch & Birch, LLP
- Main IPC: A01N43/04
- IPC: A01N43/04 ; A61K31/70 ; A61K31/7076 ; C07H19/167 ; A61K31/706 ; A61K31/7064
Abstract:
The present invention provides therapeutic agents for preventing and treating neurodegenerative diseases. These agents synergistically target both the adenosine A2A receptor (A2AR) and the equilibrative nucleoside transporter 1 (ENT1).
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