Invention Grant
- Patent Title: Polymorphic forms and co-crystals of a c-Met inhibitor
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Application No.: US15966157Application Date: 2018-04-30
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Publication No.: US10344041B2Publication Date: 2019-07-09
- Inventor: David Bauer , Matthew Bio , Melanie Cooke , Katrina W. Copeland , Matthew Peterson , Michele Potashman , Roman Shimanovich , Helming Tan
- Applicant: AMGEN, INC.
- Applicant Address: US CA Thousand Oaks
- Assignee: Amgen, Inc.
- Current Assignee: Amgen, Inc.
- Current Assignee Address: US CA Thousand Oaks
- Agency: Lucas & Mercanti, LLP
- Main IPC: C07D519/00
- IPC: C07D519/00 ; A61K31/52 ; C07C55/10 ; C07C55/12 ; C07C57/10 ; C07C57/145 ; C07C275/02

Abstract:
Provided herein are novel polymorphic forms and co-crystals of a compound useful in the treatment, prevention, or amelioration of cancer. In particular, the invention provides polymorphs and co-crystals of 6-{(1R)-1-[8-fluoro-6-(1-methyl-1H-pyrazol-4-yl)[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl}-3-(2-methoxyethoxy)-1,6-naphthyridin-5(6H)-one, which is an inhibitor of c-Met.
Public/Granted literature
- US20180244696A1 POLYMORPHIC FORMS AND CO-CRYSTALS OF A C-MET INHIBITOR Public/Granted day:2018-08-30
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